Mapping of parathyroid hormone to help patients of os

Scientists have for the first time seen clearly the dynamic structure of the receptor of human parathyroid hormone, of which the s

ecretion is closely related to diseases including osteoporosis, hypoparathyroidism, and cachexia.

The revelation provides valuable insights into discovering novel therap

eutics against such diseases, the group of researchers said at a media briefing on Friday.

Patients of osteoporosis, who the National Health Commission in October said number nearly 20 percent of Chin

ese over the age of 50, need to take medicines stimulating the human parathyroid hormone receptor.

As such medicines are polypeptide, they can only be injected rather than being orally ta

ken, which can trigger a reaction with enzymes in the mouth and become ineffective, researchers said.

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